Table 2.

Incidence rates and adjusted hazard ratios of incident CKD in stone formers versus nonstone formers in 10,678 Atherosclerosis Risk in Communities study participants

Analysis Group	Stone Former	Number in Group	Number of CKD Events	CKD Events per 1000 Person-Years (95% CI)	Model 1, Hazard Ratio (95% CI)	Model 2, Hazard Ratio (95% CI)
Baseline plus time-varying	Yes	1178	138	11.3 (9.6 to 13.4)	1.29 (1.07 to 1.54)a	1.09 (0.90 to 1.32)
	No	9500	899	7.7 (7.3 to 8.3)	1 (reference)	1 (reference)
Baseline (visit 4) only	Yes	856	104	10.4 (8.6 to 12.6)	1.21 (0.98 to 1.48)	0.99 (0.80 to 1.24)
	No	9822	945	8.0 (7.5 to 8.5)	1 (reference)	1 (reference)

Model 1 was adjusted for age, sex, race, and study center. Model 2 was adjusted for the demographic factors in model 1 as well as HDL, hypertension, urine albumin-to-creatinine ratio, eGFR, plasma uric acid (linear spline with knot at 6 mg/dl), diuretic use, smoking status, body mass index, diabetes, history of coronary heart disease, and high-sensitivity C-reactive protein. 95% CI, 95% confidence interval.

^aP=0.01.