Figure 4. eQTeL increase statistical power to detect small-effect regulatory SNPs: comparsion of effect-size of SNPs detected by eQTeL and eqtnminer.

Number of SNPs for each method was controlled. eQTeL can detect SNPs with small effect size if the regulatory potential of SNP is high. eQTeL-high-potential are subset of eeSNPs with interacting-regulatory potential=1 and eQTeL-low-potential are subset with interacting-regulatory potential<0.1.