Table 1.
Correlation between miR-449a expression and clinicopathological features of non-small cell lung cancer
| Factor | No. of cases | MiR-449a Expression | χ2 value | P value | |
|---|---|---|---|---|---|
|
| |||||
| lower | higher | ||||
| Age | |||||
| <62 | 11 | 6 | 5 | ||
| ≥62 | 19 | 9 | 10 | 0.144 | 0.705 |
| Gender | |||||
| Man | 23 | 13 | 10 | ||
| Woman | 7 | 2 | 5 | 1.677 | 0.195 |
| Smoking history | |||||
| Smoker | 18 | 13 | 5 | ||
| Non smoker | 12 | 2 | 10 | 8.889 | 0.003* |
| Histology | |||||
| Sq | 16 | 9 | 7 | ||
| Ad | 13 | 5 | 8 | ||
| Other | 1 | 1 | 0 | 1.870 | 0.469 |
| Stage | |||||
| I+II | 9 | 2 | 7 | ||
| III+IV | 21 | 13 | 8 | 3.968 | 0.046* |
| Lymph node status | |||||
| Negative | 5 | 0 | 5 | ||
| Positive | 25 | 15 | 10 | 6.000 | 0.042* |
Significant difference.
χ2 test was used to evaluate the correlation of mir-449a expression and clinical pathologic parameters.