Figure 2.

The expression of 6 lncRNAs was determined in normal renal (CTRL, n=10) and localized (n=9)/advanced (n=9) clear cell renal cell carcinoma tissue to confirm expression differences in advanced and localized carcinoma patients. lnc-CYP4A22-2/3 and lnc-ZNF180-2 were differentially expressed in malignant and normal renal tissue (both P<0.001). Furthermore, lnc-ZNF180-2 was increased (P<0.001) in advanced compared to localized clear cell renal cell carcinoma tissue. lncPEAK1.1-1 (P=0.042) also was slightly increased in advanced compared to localized tumors.