Table 2.
Relationship of p4E-BP1, EIF4E, and combined p4E-BP1/EIF4E with clinico-pathological parameters in clinically confined ccRCC
| p4E-BP1 (n = 113) | EIF4E (n = 129) | Combined (n = 111) | ||||
|---|---|---|---|---|---|---|
| Grade | -ve | +ve | -ve | +ve | -ve | +ve |
| Grade 1 & 2 | 56 | 29 | 62 | 33 | 71 | 12 |
| Grade 3 | 11 | 8 | 13 | 10 | 14 | 5 |
| Grade 4 | 3 | 6 | 6 | 5 | 5 | 4 |
| P = 0.15 | P = 0.62 | P = 0.062 | ||||
| Size | ||||||
| 4 cm and less | 11 | 7 | 16 | 6 | 14 | 2 |
| > 4 cm to 7 cm | 24 | 16 | 27 | 20 | 31 | 9 |
| > 7 to 10 cm | 26 | 11 | 26 | 14 | 31 | 6 |
| > 10 cm | 9 | 9 | 12 | 8 | 14 | 4 |
| P = 0.52 | P = 0.65 | P = 0.78 | ||||
| Stage | ||||||
| Stage 1 | 26 | 15 | 31 | 19 | 33 | 6 |
| Stage 2 | 14 | 10 | 21 | 7 | 20 | 4 |
| Stage 3 & 4 | 30 | 18 | 29 | 22 | 37 | 11 |
| P = 0.27 | P = 0.27 | P = 0.63 | ||||
| Vascular Invasion | ||||||
| (-ve) | 40 | 23 | 48 | 25 | 53 | 8 |
| (+ve) | 30 | 20 | 33 | 23 | 37 | 13 |
| P = 1 | P = 0.42 | P = 0.08 | ||||
| Capsular Invasion | ||||||
| (-ve) | 56 | 34 | 66 | 39 | 72 | 16 |
| (+ve) | 14 | 9 | 15 | 9 | 18 | 5 |
| P = 0.9 | P = 0.98 | P = 0.70 | ||||
P < 0.05 denotes significance.