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Multivariate Cox regression hazard model for time to recurrence for the composite covariate of eIF4E and p4E-BP1
| Prognostic indice | HR | 95% CI | P value |
|---|---|---|---|
| Grade 1 and 2 | 1 | ||
| Grade 3 and 4 | 3.3 | 2.0-5.2 | < 0.001 |
| Stage I and II | 1 | ||
| Stage III and IV | 2.3 | 2.3-3.6 | < 0.001 |
| eIF4E-p4E-BP1 covariate negative | 1 | ||
| eIF4E-p4E-BP1 covariate positive | 4.2 | 2.1-8.6 | < 0.001 |
Tumour size and vascular invasion were also entered into the model but were not considered significant at this step. P < 0.05 denotes significance.
