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. 2015 Jul 22;17(12):1628–1636. doi: 10.1093/neuonc/nov129

Table 4.

Screening accuracy to detect a full scale IQ < 80 based on maximum Youden's Index for each measure

Measure N Informant Cutoff Score AUC (95% CI) Sens% (95% CI) Spec% (95% CI) LR+ LR− J
BRIEFa 104 Parent >57 0.76 (0.61–0.90) 75 (51–90) 75 (64–84) 3.00 0.33 0.50
98 Teacher >59 0.82 (0.70–0.94) 79 (54–93) 77 (66–86) 3.46 0.27 0.56
SDQa 103 Child >11 0.73 (0.63–0.84) 68 (43–86) 75 (64–84) 2.74 0.42 0.43
104 Parent >14 0.78 (0.67–0.89) 55 (36–80) 87 (77–93) 4.20 0.52 0.42
99 Teacher >7 0.80 (0.70–0.94) 84 (60–96) 71 (64–84) 2.93 0.22 0.56
PedsQLb 103 Child <65 0.85 (0.77–0.93) 84 (60–96) 79 (68–86) 3.93 0.20 0.63
103 Parent <51 0.82 (0.72–0.92) 65 (41–84) 87 (77–93) 4.90 0.40 0.52

Abbreviations: AUC, area under the curve; BRIEF, Behavior Rating Inventory of Executive Functioning;34 J, Youden Index; LR+, likelihood ratio for a positive test; LR−, likelihood ratio for a negative test; PedsQL, Pediatric Quality of Life Inventory;36 SDQ, Strengths and Difficulties Questionnaire;35 Sens, sensitivity; Spec, specificity.

All AUCs were significant at P < 001.

a

Higher scores indicate increased dysfunction.

b

Higher scores indicate better quality of life.