Fig. 3.

Nephrin 1 and uromodulin levels are predictive of salt sensitivity and hypertension. Left panels: scatter plots of optical density values from WB analysis using urines from 19 controls, 16 SR and 15 SS hypertensive patients. Right panels: ROC curves were depicted with associated AUC and sensitivity and specificity at the best cut-off point. As optimal cut off point we used the one closest to top-left corner. In the scatter plots, y-axis indicates the OD of the target proteins normalized against actin values; the lines indicate the optimal cutoff value reported in the ROC curves. *0.01 < P value < 0.05; **0.001 < P value < 0.01; ***P < 0.001.