Table 2.
MALDI-TOF identification of S-glutathionylated buccal cell proteins following H2O2 exposure.
| Protein | MW (kDa) | Protein function |
|---|---|---|
| GSTP1 | 24 | Phase II metabolism; S-glutathionylation. |
| Inter-α trypsin inhibitor | 75 | Plasma protease inhibitor. |
| B4GALNT2 | 20 | β-1,4-N-acetyl-galactosaminyl transferase 2 isoform c; protein glycosylation; negative regulation of cell adhesion. |
| GRAF | 52 | rho GTPase activating protein 26; associates with focal adhesion kinase. |
| PAR6 | 65 | Partitioning defective 6 homolog γ; cell division and polarization. |
| Flaggrin | 125 | Epithelial structure; mucosal S100 fusion type protein. |
| Plakoglobin | 125 | γ-Catenin; complexes with cadherins. |
| Reticulon-2 | 65, 20 | ER protein promotes membrane curvature, nuclear pore complex and vesicle formation. |
| Actin | 42 | Microfilament formation. |
| Histone H1 | 20 | Chromatin structure. |
| Lactotransferrin | 65 | Antimicrobial activity; part of the innate defense at the mucoses. |
| Complement | 52, 42 | Innate immunity. |
| Albumin | 75, 65, 42 | Blood globular protein. |