Table 1.
Immunogenicity findings of the trivalent seasonal influenza vaccine FluvalAB in adult subjects (18–60 years)
| Year | Strain | Seropositivity (CHMP criterion: >70%) | Seroconversion (CHMP criterion: >40%) | GMT increase (CHMP criterion: >2·5) | CHMP requirement met |
|---|---|---|---|---|---|
| 1997 | A(H1N1) A(H3N2) B | 84% 85% 75% | 41% 46% 43% | 3·0 3·4 3·3 | Yes |
| 1998 | A(H1N1) A(H3N2) B | 86% 82% 86% | 56% 50% 68% | 4·7 3·6 4·2 | Yes |
| 2000 | A(H1N1) A(H3N2) B | 84% 70% 72% | 72% 56% 62% | 3·5 3·3 3·0 | Yes |
| 2001 | A(H1N1) A(H3N2) B | 84% 84% 79% | 47% 46% 49% | 3·4 3·1 3·4 | Yes |
| 2002 | A(H1N1) A(H3N2) B | 88% 90% 80% | 62% 66% 54% | 3·3 3·9 3·9 | Yes |
| 2004 | A(H1N1) A(H3N2) B | 72% 76% 86% | 46% 54% 48% | 3·4 2·6 3·6 | Yes |
| 2005 | A(H1N1) A(H3N2) B | 84% 78% 80% | 44% 42% 48% | 3·1 3·0 3·2 | Yes |
| 2006 | A(H1N1) A(H3N2) B | 88% 82% 77% | 43% 47% 45% | 2·8 3·5 3·0 | Yes |
| 2007 | A(H1N1) A(H3N2) B | 76% 80% 76% | 52% 52% 50% | 5·4 4·0 3·9 | Yes |