Table 2.
Immunogenicity findings of the trivalent seasonal influenza vaccine FluvalAB in elderly persons (>60 years)
| Year | Strain | Seropositivity (CHMP criterion: >60%) | Seroconversion (CHMP criterion: >30%) | GMT increase (CHMP criterion: >2) | CHMP requirement met |
|---|---|---|---|---|---|
| 1997 | A(H1N1) A(H3N2) B | 52% 68% 58% | 32% 38% 31% | 2·9 2·8 3·1 | Yes |
| 1998 | A(H1N1) A(H3N2) B | 62% 70% 78% | 36% 44% 58% | 2·9 2·7 4·0 | Yes |
| 2000 | A(H1N1) A(H3N2) B | 68% 70% 74% | 44% 52% 56% | 2·6 2·8 2·8 | Yes |
| 2001 | A(H1N1) A(H3N2) B | 67% 69% 70% | 40% 38% 41% | 2·9 2·8 2·7 | Yes |
| 2002 | A(H1N1) A(H3N2) B | 72% 82% 88% | 38% 36% 44% | 3·1 3·2 3·9 | Yes |
| 2004 | A(H1N1) A(H3N2) B | 72% 70% 82% | 38% 32% 38% | 3·3 3·1 3·2 | Yes |
| 2005 | A(H1N1) A(H3N2) B | 72% 70% 82% | 32% 36% 42% | 2·4 2·7 3·5 | Yes |
| 2006 | A(H1N1) A(H3N2) B | 75% 78% 70% | 37% 40% 35% | 2·7 3·1 2·8 | Yes |
| 2007 | A(H1N1) A(H3N2) B | 68% 68% 68% | 42% 50% 42% | 3·0 3·1 2·9 | Yes |