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. 2015 Nov 4;15:256. doi: 10.1186/s12866-015-0586-2

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© Assato et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Primary sequence analysis. An “*” (asterisk) indicates positions that have a single, fully conserved residue; A “:” (colon) indicates conservation between groups with strongly similar properties - scoring > 0.5 in the Gonnet PAM 250 matrix; A “.” (period) indicates conservation between groups of weakly similar properties - scoring = < 0.5 in the Gonnet PAM 250 matrix. The code of colors according to their physicochemical properties are as follows: red, small and hydrophobic (AVFPMILW); blue, acidic (DE); magenta, basic (RK); and green, (STYHCNGQ)