Table 3.
Characteristics | Severe outcome n/N (%) | Unadjusted OR | P value | 95% CI |
---|---|---|---|---|
Age (years) | ||||
18–49 | 40/108 (37) | 1·68 | 0·16 | 0·82–3·46 |
≥50 | 14/54 (26) | |||
Sex | ||||
Female | 30/102 (29) | 0·63 | 0·17 | 0·32–1·22 |
Male | 24/60 (40) | |||
Race/ethnicity | ||||
White, non‐Hispanic | 22/55 (40) | |||
Hispanic | 11/38 (29) | 0·61 | 0·27 | 0·25–1·48 |
Black, non‐Hispanic | 7/23 (30) | 0·66 | 0·43 | 0·23–1·86 |
Asian–Pacific Islander, non‐Hispanic | 6/12 (50) | 1·50 | 0·53 | 0·43–5·25 |
Asthma classification | ||||
Intermittent | 24/76 (32) | |||
Mild persistent | 10/30 (33) | 1·08 | 0·86 | 0·44–2·66 |
Moderate persistent | 5/9 (56) | 2·71 | 0·15 | 0·67–10·99 |
Severe persistent | 3/11 (27) | 0·81 | 0·77 | 0·20–3·34 |
Obesity (BMI ≥ 30 in age ≥ 20 years) | ||||
Present | 16/46 (35) | 0·40 | 0·09 | 0·14–1·15 |
Absent | 12/21 (57) | |||
Pregnancy (female aged 15–44 years) | ||||
Present | 5/13 (38) | 1·53 | 0·72 | 0·39–5·95 |
Absent | 9/31 (29) | |||
Any chronic condition | ||||
Present | 43/128 (34) | 0·06 | ||
Absent | 0/8 (0) | |||
Cancer | ||||
Present | 1/4 (25) | 0·66 | >0·99 | 0·07–6·50 |
Absent | 53/158 (34) | |||
Cardiac diseases | ||||
Present | 10/31 (32) | 0·89 | 0·80 | 0·38–2·08 |
Absent | 41/118 (35) | |||
Chronic obstructive pulmonary disease | ||||
Present | 9/31 (29) | 0·78 | 0·57 | 0·33–1·84 |
Absent | 45/131 (34) | |||
Diabetes | ||||
Present | 8/26 (31) | 0·87 | 0·76 | 0·35–2·15 |
Absent | 46/136 (34) | |||
HIV | ||||
Present | 2/5 (40) | 1·35 | >0·99 | 0·22–8·31 |
Absent | 52/157 (33) | |||
Neuromuscular | ||||
Present | 11/21 (52) | 2·39 | 0·06 | 0·94–6·07 |
Absent | 41/130 (32) | |||
Renal diseases | ||||
Present | 7/11 (64) | 3·87 | 0·04 | 1·08–13·87 |
Absent | 47/151 (31) | |||
Infiltrates on chest radiograph | ||||
Present | 41/76 (54) | 9·71 | <0·01 | 3·93–23·99 |
Absent | 7/65 (11) | |||
Antivirals | ||||
Administered within 48 hours | 10/45 (22) | 0·37 | 0·02 | 0·15–0·89 |
Not administered within 48 hours | 37/85 (44) |
OR, odds ratio; CI, confidence interval; HIV, human immunodeficiency virus infection.
Defined as ICU stay or death.