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. 2013 Jul 15;7(6):1343–1349. doi: 10.1111/irv.12120

Table 3.

Prevalence of severe outcomesa by selected characteristics among asthma patients who were hospitalized or who died with 2009 pandemic influenza A (H1N1) infection

Characteristics Severe outcome n/N (%) Unadjusted OR P value 95% CI
Age (years)
18–49 40/108 (37) 1·68 0·16 0·82–3·46
≥50 14/54 (26)
Sex
Female 30/102 (29) 0·63 0·17 0·32–1·22
Male 24/60 (40)
Race/ethnicity
White, non‐Hispanic 22/55 (40)
Hispanic 11/38 (29) 0·61 0·27 0·25–1·48
Black, non‐Hispanic 7/23 (30) 0·66 0·43 0·23–1·86
Asian–Pacific Islander, non‐Hispanic 6/12 (50) 1·50 0·53 0·43–5·25
Asthma classification
Intermittent 24/76 (32)
Mild persistent 10/30 (33) 1·08 0·86 0·44–2·66
Moderate persistent 5/9 (56) 2·71 0·15 0·67–10·99
Severe persistent 3/11 (27) 0·81 0·77 0·20–3·34
Obesity (BMI ≥ 30 in age ≥ 20 years)
Present 16/46 (35) 0·40 0·09 0·14–1·15
Absent 12/21 (57)
Pregnancy (female aged 15–44 years)
Present 5/13 (38) 1·53 0·72 0·39–5·95
Absent 9/31 (29)
Any chronic condition
Present 43/128 (34) 0·06
Absent 0/8 (0)
Cancer
Present 1/4 (25) 0·66 >0·99 0·07–6·50
Absent 53/158 (34)
Cardiac diseases
Present 10/31 (32) 0·89 0·80 0·38–2·08
Absent 41/118 (35)
Chronic obstructive pulmonary disease
Present 9/31 (29) 0·78 0·57 0·33–1·84
Absent 45/131 (34)
Diabetes
Present 8/26 (31) 0·87 0·76 0·35–2·15
Absent 46/136 (34)
HIV
Present 2/5 (40) 1·35 >0·99 0·22–8·31
Absent 52/157 (33)
Neuromuscular
Present 11/21 (52) 2·39 0·06 0·94–6·07
Absent 41/130 (32)
Renal diseases
Present 7/11 (64) 3·87 0·04 1·08–13·87
Absent 47/151 (31)
Infiltrates on chest radiograph
Present 41/76 (54) 9·71 <0·01 3·93–23·99
Absent 7/65 (11)
Antivirals
Administered within 48 hours 10/45 (22) 0·37 0·02 0·15–0·89
Not administered within 48 hours 37/85 (44)

OR, odds ratio; CI, confidence interval; HIV, human immunodeficiency virus infection.

a

Defined as ICU stay or death.