Fig. 3.

Proliferation capacity of GC lines in relation to subtype and survival. (A) Kaplan–Meier comparing the survival of patients in relationship to the TCGA molecular subtype of the GC lines established from their tumors. (B) Growth curves for 31 GC lines of differing TCGA molecular subtypes. Based on their proliferative capacity on day 7, the cell lines below the first quartile were designated as “low proliferation”, between the first and third quartiles as “intermediate proliferation”, and above the third quartile as “high proliferation”. (C) The GC lines categorized were listed in the order of highest to lowest proliferative capacity. (D) Analysis (Student's t-test) of the proliferative capacity of GC lines in relationship to their TCGA molecular subtype. (E) Kaplan–Meier plot comparing the survival of patients with GBM in relationship to the proliferative capacity (high, intermediate, and low) of the corresponding GC lines. Log-rank test, *p < 0.05.