Table 4.
Overview of some suspended micro- and nanochannel resonators.
Resonator Type | Year | Dimensions of Resonator and Channel (Length × Width × Height) | Actuation/Sensing Method | Resonant Frequency | Quality Factor | Limit of Detection (Sensitivity) | Target/Application | Reference |
---|---|---|---|---|---|---|---|---|
Microchannel | 2003 | 300μm × N/A × N/A | Electrostatic/optical | ~42.7 kHz (air); 40.1 kHz (2-propanol); 39.6 kHz (water) | ~90 (air) | Avidin and biotinylated bovine serum albumin | Burg et al. [30] | |
N/A | ||||||||
2006 | 300 × 33 × 7 μm | Electrostatic/optical | ~33.5 kHz | ~300–700 (vacuum); ~85 (air) | 0.8 ng/cm2 | Avidin and biotinylated bovine serum albumin | Burg et al. [170] | |
200 × 33 × 7 μm | ||||||||
2007 | 200 × 33 × 7 μm | Electrostatic/optical | 220.5 kHz (air); 209.6 kHz (water) | 15,000 | 0.7 ng/mL | Goat anti-mouse IgG molecules | Burg et al. [163] | |
N/A × 8 × 3 μm | ||||||||
2010 | 12 × 0.1 × 0.03 mm | N/A | ~200 kHz | 15,000 | 10 ng/mL | Activated leukocyte cell adhesion molecule (ALCAM) | von Muhlen et al. [171] | |
2013 | 200 × 8 × 3 μm | Optical/optical | 2–11,000 MHz | 1.6E8 | N/A | Water | Bahl et al. [172] | |
2011 | 406 × 28.5 × 12 μm | Piezoresistive/optical | 92.1 kHz | 10,850 | 18.1 fg | Budding yeast cells | Lee et al. [173] | |
N/A × 7.9 × 8 μm | ||||||||
2013 | 200 × 20 × N/A μm | Piezoresistive/optical | ~137.7 kHz | ~15,000 | 16 Hz/kg/m3 | very light solvents to very viscous and sticky crude oil samples | Khan et al. [167] | |
N/A × 4 × 3 μm | ||||||||
2014 | 60 × 36 × 7 μm | Feedback loop/optical | 1.17 MHz | ~23,000 (gas); ~6000 (liquid) | ~30 fg | polystyrene nanoparticles | Modena et al. [169] | |
N/A × 8 × 3 μm | ||||||||
2013 | 300 × 30 × 30 μm | Thermal/optical | 2.21 MHz (ambient atmosphere); 1.25 MHz (water) | 190 (ambient atmosphere); 170 (water) | 8.6 ppm/μW | Biological molecules and individual cells | Toda et al. [166] | |
Nanochannel | 2010 | 20 μm × 650 nm~2.5 μm × 107 nm | Thermal/optical | ~25 kHz | 1300–7000 (before filling) | 2 fg | Ethanol, H2O and D2O | Barton et al. [161] |
2010 | 50 × 10 × 1.3 μm | Electrostatic/optical | ~630 kHz | ~8000 | 27 ag | Ethanol, H2O and D2O | Lee et al. [174] | |
N/A × 2 μm × 700 nm |