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. 2015 Nov 4;14:437. doi: 10.1186/s12936-015-0969-8

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© Penny et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Predicted and observed efficacy against clinical disease by three-monthly periods by trial site for the 6–12 weeks cohort with booster using best-fitted vaccine profile. Reported efficacy (mean and 95 % CI) in the trial site is indicated by black circles. Prediction estimates in purple (median and 95 % CI)