Table 1.
Route of highly pathogenic avian influenza virus H5N1 infection of cats, body temperature, and virus excretion
| Animal no. | EID50 | Route of infection | Body temperature in °C (dpi) | Pharyngeal swab (dpi) | Rectal swabs (dpi) | Euth (dpi) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | 0 | 2 | 4 | 0 | 2 | 4 | ||||
| 081 | 106 | Oc‐na* | 38·8 | 39·9 | 39·3 | 40·0 | 39·0 | − | + | + | − | − | − | 6 |
| 114 | 106 | Oc‐na* | 38·4 | 39·1 | 40·3 | 40·3 | 40·2 | − | − | + | − | − | + | 6 |
| 256 | 106 | Oc‐na* | 38·8 | 38·4 | 39·7 | 39·3 | 39·1 | − | + | + | − | − | ++ | 6 |
| 301 | 106 | Oc‐na* | 38·4 | 39·4 | 39·1 | 40·3 | 39·5 | − | + | + | − | + | − | 6 |
| 262 | 107 | Ga‐in** | 38·5 | 39·5 | 39·7 | 38·9 | nd | − | + | + | − | − | − | 4 |
| 879 | 107 | Ga‐in** | 38·6 | 40·1 | 39·8 | 40·9 | 38·2 | − | + | + | − | + | − | 6 |
| 800 | 106 | i.v.*** | 39·5 | 41·0 | 40·7 | 40·6 | nd | − | + | + | − | + | ++ | 4 |
| 633 | 106 | i.v.*** | 39·2 | 40·6 | 41·3 | 40·8 | nd | − | + | + | − | − | + | 4 |
| 117 | 0 | Control† | 38·7 | 38·9 | 38·9 | 38·5 | 38·7 | − | − | − | − | − | − | 6 |
| 848 | 0 | Control† | 38·6 | 38·8 | 38·7 | 38·7 | 38·4 | − | − | − | − | − | − | 6 |
Elevated body temperatures (above 39°C) are underlined. The rRT‐PCR results are given as: +++ (Ct values of <24), ++ (Ct values of 24 to <31), and + (Ct values of 31 to <38); days post‐infection (dpi); not done (nd).
*Oculo‐nasopharyngeal.
**Gastrointestinal.
***Intravenous.
†Uninfected control.