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. 2010 Aug 24;4(6):379–386. doi: 10.1111/j.1750-2659.2010.00173.x

Table 4.

 Blood chemical parameters after highly pathogenic avian influenza virus H5N1 infection of cats

Animal no. EID50 Route of infection Blood parameter* Units Day 0 Day 4 p.i.
081 106 Oculo‐nasopharyngeal AST (U/l) 42 796
ALT (U/l) 44 642
CPK (U/l) 250 >2000
TBIL (mg/dl) 0·6 3·6
256 106 Oculo‐nasopharyngeal AST (U/l) 34 >1000
ALT (U/l) 42 >1000
CPK (U/l) 137 1691
TBIL (mg/dl) 0·1 2·5
262 107 Gastrointestinal (capsule) AST (U/l) 74 223
ALT (U/l) 98 502
CPK (U/l) 144 >2000
TBIL (mg/dl) 0·7 1·9
879 107 Gastrointestinal (capsule) AST (U/l) 18 113
ALT (U/l) 71 118
CP (U/l) 143 338
TBIL (mg/dl) 0·4 3·9
800 106 Intravenous AST (U/l) 23 807
ALT (U/l) 82 >1000
CPK (U/l) 115 >2000
TBIL (mg/dl) 0·6 2·1
633 106 Intravenous AST (U/l) 69 >1000
ALT (U/l) 96 >1000
CPK (U/l) 134 >2000
TBIL (mg/dl) 0·6 5·3
117 0 Uninfected control AST (U/l) 28 51
ALT (U/l) 49 58
CPK (U/l) 279 196
TBIL (mg/dl) 0·4 0·5
848 0 Uninfected control AST (U/l) 129 56
ALT (U/l) 42 84
CPK (U/l) 308 252
TBIL (mg/dl) 0·7 0·6

*Physiological reference values are aspartate aminotransferase (AST) 18–51 U/l; alanine aminotransferase (ALT) 22–84 U/l; creatine phosphokinase (CPK) 87–309 U/l; total bilirubin (TBIL) 0·1–0·5 mg/dl.