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Full-field binocular LDTs (OU) for patients 2, 3, and 4 (P2, P3, P4). Upward arrow (↑) indicates the subject surpassed the highest luminance stimulus (ceiling effect). The results of all three LCA-CEP290 patients, plotted here, demonstrate greater aversion to the shorter-wavelength stimuli than to longer-wavelength stimuli, suggesting the influence of melanopsin on their LDTs. P6 is not shown because she failed to stop the test at the highest luminance for all three chromatic stimuli.
