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. Author manuscript; available in PMC: 2016 Dec 28.
Published in final edited form as: Cancer Lett. 2015 Sep 26;369(2):261–265. doi: 10.1016/j.canlet.2015.09.011

Figure 1.

Figure 1

Pedigree of family reported here, whose germline DNA contained a nonsense mutation in BAP1 exon 15 (c.1938T>A). The family of the proband (III-07, arrow) shows numerous malignancies, including six family members (I-02, II-03, III-05, III-07, III-09, and III-10) with two or more primary cancers. Predominant tumors include malignant mesothelioma and cutaneous melanoma, each observed in five family members.