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. 2015 Nov 5;10(11):e0141482. doi: 10.1371/journal.pone.0141482

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© 2015 Bonnet et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 9 — These biomarkers correspond to the most strongly expressed genes in a specific cell type and stage (PDO, PMO, SCO, SAO, PDG, PMG, SCG, SAG). They were selected using pairwise comparisons (nbinom Test) comparing each stage to the others including multi-tissue samples (FDR<5% and a fold change >3 for granulosa samples and a fold change >-10 for oocyte samples). Their differential expression was confirmed by qRT-PCR. Gene names marked in red are genes expressed in granulosa cells and gene names marked in blue are genes expressed in oocytes. Gene names marked in black are genes expressed both in oocytes and granulosa cells.