Table 2.

Results of trial C208 for bedaquiline

Drug + dose	Number of patients in mITT group	6-month sputum conversion	P-value	Median time to culture conversion
Bedaquilinea + 5 drug regimen	66	78.80%	0.009	12 weeks
Placebo + 5 drug regimen	66	57.60%		18 weeks

Notes:

^aGiven at 400 mg daily for the first 2 weeks, followed by 200 mg three times per week for the remaining 22 weeks. Data devised from Diacon et al.¹⁶

Abbreviation: mITT, modified intention to treat.