Figure 2.

Cytotoxic effect of As₄S₄ in combination with cisplatin on gastric and colon cancer cells.

Notes: (A and B) AGS cells were treated with As₄S₄ 1.5 μM alone or in combination with cisplatin 7.5 μg/mL for 24 and 48 hours. (C and D) MGC803 cells were treated with As₄S₄ 1 μM alone or in combination with cisplatin 2 μg/mL for 24 and 48 hours. (E and F) SW480 cells were treated with As₄S₄ 5 μM alone or in combination with cisplatin 7.5 μg/mL for 24 and 48 hours. (G and H) HCT116 cells were treated with As₄S₄ 5 μM alone or in combination with cisplatin 7.5 μg/mL for 24 and 48 hours. Data represent the mean ± standard deviation of three independent experiments and the relative cell viability was expressed as the percentage of untreated well. The data represent one of three experiments with similar results. ^**P<0.01, ^***P<0.001.

Abbreviations: As₄S₄, arsenic sulfide; h, hours.