Figure 3.

V-SVZ adult stem cells and cortical astrogenesis. V-SVZ adult stem cells are regenerating cells (A) that have recently shown to proliferate into protective reactive astrocytes after injury (B) and contribute to the glial scar in the cortex (C).92 (D) It is also known that they can contribute to adult astrogenesis. However, it is unclear whether the reactive astrocytes they produce can proliferate locally (E), although this proliferation likely occurs if derived locally from a mature astrocyte (F). It is also uncertain whether reactive astrocytes produced by the V-SVZ can become mature protoplasmic astrocytes (G), which may also be able to proliferate (H).