. Author manuscript; available in PMC: 2015 Nov 5.

Published in final edited form as: Future Oncol. 2012 Jun;8(6):703–711. doi: 10.2217/fon.12.57

Table 1.

Biomarkers for breast cancer prognosis and prediction of response to therapy.

Assay	Method	Marker	Prognosis	Predictor	Patient eligibility
GGI	Microarray	97 genes	Yes	Yes	Node⁻/ER⁺
PAM50™	qRT-PCR	55 genes	Yes	Yes	Node⁻/ER⁺
IHC4	IHC	4 genes	Yes	ND	Node⁻/ER⁺
Mammostrat^®	IHC	5 genes	Yes	ND	Node⁻/ER⁺
MammaPrint^®	Microarray	70 genes	Yes	Yes	Node^±/ER^±
Oncotype DX^®	qRT-PCR	21 genes	Yes	Yes	Node⁻/ER⁺
Immune function genes	qRT-PCR	5 immune function genes and CTAs	In trial	In trial	Node^±/ER^±

±: Positive and negative; −: Negative; +: Postitive; CTA: Cancer testis antigen; IHC: Immunohistochemistry; ND: Not determined; qRT: Quantitative reverse transcriptase.