Table 2. Response to exposure by mouse strain.

Mouse strain	Exposure	Cytokine production	Disease phenotype
C57BL/6	Carbon tetrachloride (liver)	Th1 cytokines	Minimal fibrosis
BALB/c	Carbon tetrachloride (liver)	Th2 cytokines	Severe fibrosis [32]
C57BL/6	Nitric oxide synthase blocker	Ratio IFNγ/IL4 = 173	Hypertension with no increase in cardiac collagen
BALB/c	Nitric oxide synthase blocker	Ratio IFNγ/IL4 = 21	Hypertension with increased cardiac collagen and collagen cross-linking [199]
C57BL/6	Angiotensin II	Not reported	No disease
BALB/c	Angiotensin II	Not reported	Dilated cardiomyopathy [200]