Table 1. Comparison of baseline characteristics and co-morbidities between patients with and without OAC at baseline.
| Without OAC | With OAC | p value | |
|---|---|---|---|
| Number | N = 1,541 | N = 1,751 | |
| <Baseline characteristics> | |||
| Female sex | 673 (44%) | 651 (37%) | <0.01 |
| Age (years) | 73.1 ± 12.5 | 74.1 ± 9.2 | 0.01 |
| Advanced age (≥75 years) | 759 (49%) | 929 (53%) | 0.03 |
| Body weight (kg) | 57.9 ± 13.2 | 60.1 ± 13.3 | <0.01 |
| BMI (kg/m2) | 22.7 ± 4.0 | 23.3 ± 4.0 | <0.01 |
| Underweight (BMI <18.5 kg/m2) | 180 (14%) | 138 (9%) | <0.01 |
| Systolic blood pressure (mmHg) | 126.3 ± 19.3 | 123.2 ± 18.6 | <0.01 |
| Diastolic blood pressure (mmHg) | 70.9 ± 13.0 | 70.2 ± 12.7 | 0.10 |
| Heart rate (beats/min) | 78.1 ± 16.0 | 77.4 ± 15.6 | 0.17 |
| Type of atrial fibrillation | |||
| paroxysmal | 963 (63%) | 618 (35%) | |
| Persistent | 111 (7%) | 148 (9%) | <0.01 |
| Permanent | 467 (30%) | 985 (56%) | |
| Antiplatelet therapy at baseline | 535 (35%) | 433 (25%) | <0.01 |
| <Co-morbidities> | |||
| Previous stroke/SE/TIA | 218 (14%) | 466 (27%) | <0.01 |
| Heart failure | 298 (19%) | 580 (33%) | <0.01 |
| Hypertension | 905 (59%) | 1,116 (64%) | <0.01 |
| Diabetes mellitus | 322 (21%) | 442 (25%) | <0.01 |
| Dyslipidemia | 641 (42%) | 785 (45%) | 0.06 |
| Coronary artery disease | 236 (15%) | 251 (14%) | 0.43 |
| Valvular heart disease | 202 (13%) | 389 (22%) | <0.01 |
| Cardiomyopathy | 27 (2%) | 69 (4%) | <0.01 |
| Peripheral artery disease | 58 (4%) | 80 (5%) | 0.25 |
| Chronic kidney disease | 479 (31%) | 661 (38%) | <0.01 |
| Anemia | 552 (39%) | 582 (35%) | 0.07 |
| COPD | 67 (4%) | 95 (5%) | 0.15 |
| History of major bleeding | 44 (3%) | 36 (2%) | 0.14 |
Categorial data are presented as number (%). Continuous data are presented as mean ± standard deviation. OAC: oral anticoagulants, BMI: body mass index, SE: systemic embolism, TIA: transient ischemic attack, COPD: chronic obstructive pulmonary disease.