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. Author manuscript; available in PMC: 2016 Aug 26.
Published in final edited form as: Small. 2015 May 12;11(32):3962–3972. doi: 10.1002/smll.201500288

Figure 4.

Figure 4

In vivo anticancer effect of m2 on the A2780cisR subcutaneous xenograft. a) Tumor growth curves of the mice receiving intravenous injection of PBS, 2, or m2 (n = 6). b) Photograph of the excised tumors on day 15. c) Weights of the excised tumors on Day 15 (n = 6). d) The percentage of TUNEL-positive cells in tumor tissues (n = 3). e) Representative CLSM images of TUNEL assays of tumor tissues. DNA fragment in apoptotic cells was stained with fluorescein-conjugated deoxynucleotides (green) and the nuclei were stained with DAPI (blue). Scale bars: 50 µm. f) Representative images of histological assays of tumor tissues. Scale bars: 100 µm. Statistical significance: **P < 0.01 and ***P < 0.001 compared to the control group (PBS), ###P < 0.001 compared to the 2-treated group.