Figure 6. The L-type calcium channel blocker diltiazem (DIZ) prevents the effects of cPTH.
a relative frequency of BM Th17 cells, b IL-17A mRNA levels in BM CD4+ cells c-d expression of RORα and RORγt mRNA in BM CD4+ cells, e-j µCT indices of bone volume and structure. k,l. Serum levels of CTX and P1NP. Data are shown as mean ± SEM. n = 12 mice per group. All data passed the Shapiro-Wilk normality test and were analyzed by 2-Way ANOVA. *=p<0.05, **=p<0.01, ***=p<0.001 and ****=p<0.0001 compared to the corresponding vehicle group. ## = p<0.01 compared to the DIZcPTH group.