Figure 5.
Predicted clustered Pcdh glycosylation sites largely do not overlap with the identified antiparallel interfaces. N- (magenta) or O- (black) glycosylation sites predicted in at least five human clustered Pcdh isoforms or a single C-type isoform and O-mannosylation sites (purple) from the SimpleCell strategy (Vester-Christensen et al., 2013) in clustered Pcdh EC repeats are overlaid with the observed interfaces (A1 EC12, lilac; A1 EC23, blue; C3 EC1, yellow; C3 extended, green; and A1 EC23 and C3 extended overlapping, orange). The left and right panels are related by a 180° rotation; numbering corresponds to mouse PcdhγA1.