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. 2015 Nov 5;2:10. doi: 10.1186/s40348-015-0021-7

Table 1.

Experimental animals and histology results

Number Stent type Weight at implant Number of re-dilatations Time of re-dilatation Histology results
Grams Proliferationa Granulocytesb Lymphocytesb Histocytes/FBRb
1 Bx Sonic 4.300 1 1 month + ++ ++ +
2 Bx Sonic 4.170 1 6 months + ++ ++ +
3 Bx Sonic 3.900 1 1 month + ++ ++ +
4 Bx Sonic 4.000 1 1 month ++ + ++ +
5 Bx Sonic 4.300 1 1 month + ++ ++ +
6 Bx Sonic 4.700 1 1 month + ++ ++ +
7 Cypher Select 4.760 1 1 month + ++ ++ +++
8 Cypher Select 4.310 1 6 months + + + ++
9 Cypher Select 4.110 1 1 month + ++ ++ +++

FBR foreign-body reaction

aGrading of the extent of granulation tissue with the lumen of the stents: 0 – no proliferation; + − lumen obstruction 1–25 %; ++ − lumen obstruction 26–50 %; +++ − lumen obstruction >50 %

bGrading of inflammatory reactions describing the presence of different cell types around the stent struts: 0 – no inflammatory cells; + − light, noncircumferential infiltrate; ++ − localized, moderate to dense cellular aggregate; +++ − circumferential, dense cell infiltration