Table 1.
Experimental animals and histology results
| Number | Stent type | Weight at implant | Number of re-dilatations | Time of re-dilatation | Histology results | |||
|---|---|---|---|---|---|---|---|---|
| Grams | Proliferationa | Granulocytesb | Lymphocytesb | Histocytes/FBRb | ||||
| 1 | Bx Sonic | 4.300 | 1 | 1 month | + | ++ | ++ | + |
| 2 | Bx Sonic | 4.170 | 1 | 6 months | + | ++ | ++ | + |
| 3 | Bx Sonic | 3.900 | 1 | 1 month | + | ++ | ++ | + |
| 4 | Bx Sonic | 4.000 | 1 | 1 month | ++ | + | ++ | + |
| 5 | Bx Sonic | 4.300 | 1 | 1 month | + | ++ | ++ | + |
| 6 | Bx Sonic | 4.700 | 1 | 1 month | + | ++ | ++ | + |
| 7 | Cypher Select | 4.760 | 1 | 1 month | + | ++ | ++ | +++ |
| 8 | Cypher Select | 4.310 | 1 | 6 months | + | + | + | ++ |
| 9 | Cypher Select | 4.110 | 1 | 1 month | + | ++ | ++ | +++ |
FBR foreign-body reaction
aGrading of the extent of granulation tissue with the lumen of the stents: 0 – no proliferation; + − lumen obstruction 1–25 %; ++ − lumen obstruction 26–50 %; +++ − lumen obstruction >50 %
bGrading of inflammatory reactions describing the presence of different cell types around the stent struts: 0 – no inflammatory cells; + − light, noncircumferential infiltrate; ++ − localized, moderate to dense cellular aggregate; +++ − circumferential, dense cell infiltration