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. 2015 Nov 4;35(44):14783–14793. doi: 10.1523/JNEUROSCI.2980-15.2015

Figure 4.

Figure 4.

Neutrophil activating factors are attenuated in CD36-null hosts. A, mRNA expression of Cxcl1, Cxcl2, Cxcl5, Il-1β, Csf2, and Csf3, in ischemic brain from WT and CD36 KO mice 24 and 72 h after MCAo or Sham surgery (n = 5–7 mice/group). Values are mean ± SE. *p < 0.05 versus WT. B, Cxcl1, Cxcl2, and Csf3 mRNA expression assessed in flow cytometric sorted microglia and endothelial cells (EC) from WT and CD36 KO mice 24 h after MCAo (n = 3 pool/group, with n = 3 mice/pool). Cxcl1, Cxcl2, and Csf3 mRNA expression is reduced in endothelial cells (EC) of CD36 KO mice. No changes in the microglial expression are observed between WT and CD36 KO mice. *p < 0.05 versus WT. Values are mean ± SE.