Table 2.
Biophysical properties of Kv2s with AP and Inm treatment
| Control | +AP | +Inm | |
|---|---|---|---|
| Kv2.1 activation | |||
| V1/2 (mV) | 1.1 ± 0.8 | −9.4 ± 2.8 | −9.6 ± 2.0 |
| k | 9.8 ± 0.9 | 6.6 ± 0.4 | 8.0 ± 0.9 |
| n | 5 | 7 | 6 |
| Kv2.2 activation | |||
| V1/2 (mV) | −6.1 ± 2.4 | −6.9 ± 3.5 | −6.1 ± 3.8 |
| k | 7.4 ± 1.5 | 7.5 ± 0.9 | 8.1 ± 0.5 |
| tau (+ 60 mV) (ms) | 17.4 ± 1.6 | 19.5 ± 0.8 | 14.7 ± 1.0 |
| n | 6 | 7 | 6 |
| Kv2.2 inactivation | |||
| V1/2 (mV) | −30.8 ± 5.2 | −29.7 ± 2.2 | −29.3 ± 3.8 |
| k | 6.0 ± 0.4 | 6.1 ± 1.5 | 5.7 ± 0.3 |
| n | 6 | 5 | 6 |
| Kv2.2 deactivation | |||
| tau1 (−30 mV) (ms) | 28.3 ± 2.2 | 27.3 ± 2.0 | 26.6 ± 0.8 |
| tau2 (−30 mV) (ms) | 117.1 ± 10.2 | 118.6 ± 14.4 | 134.7 ± 7.0 |
| n | 5 | 5 | 6 |
Values in bold are significantly different from control values.