Table 2.
Characteristics of patients with nonalcoholic fatty liver disease, divided according to nonalcoholic steatohepatitis and steatosis (mean + SD)
| Parameter | All patients (n = 235) | NASH | Steatosis | P value |
| Age (yr) | 45.3 + 11.9 | 45.9 + 12.4 | 43.8 + 10.4 | 0.2 |
| Gender (male/female) | 91/144 | 67/101 | 24/43 | 0.6 |
| Race (% caucasian) | 65.1 | 64.9 | 65.7 | 0.1 |
| BMI (kg/m2) | 37.7 + 11.5 | 37 + 10.6 | 39.4 + 13.7 | 0.17 |
| Hypertension, n (%) | 114 (48.5) | 82 + 48.8 | 32 + 63.9 | 1 |
| Dyslipidemia, n (%) | 139 (68.8) | 100 (70.9) | 39 (63.9) | 0.3 |
| Metabolic syndrome, n (%) | 115 + 53.7 | 67 (42.7) | 32 (56.1) | 0.08 |
| Platelets | 258 + 73.5 | 247 + 72.1 | 283 + 71.1 | < 0.01 |
| INR | 0.996 + 0.162 | 1 + 0.178 | 0.98 + 0.112 | 0.3 |
| Protein (g/dL) | 7.39 + 0.762 | 7.39 + 0.733 | 7.37 + 0.714 | 0.8 |
| Albumin (g/dL) | 4.27 + 0.536 | 4.27 + 0.555 | 4.26 + 0.487 | 0.8 |
| AST (U/L) | 49.8 + 34.5 | 54.2 + 36.3 | 38.3 + 26.1 | < 0.01 |
| ALT (U/L) | 72.6 + 58.5 | 78.7 + 63.1 | 57 + 40.7 | 0.01 |
| Bilirubin (mg/dL) | 0.668 + 0.416 | 0.71 + 0.456 | 0.567 + 0.275 | 0.01 |
| Alkaline Phosphate | 96.7 + 61.8 | 100 + 70.9 | 88.3 + 28.3 | 0.1 |
| Total cholesterol (mg/dL) | 200 + 47.3 | 202 + 48.6 | 197 + 44.5 | 0.5 |
| HDL cholesterol (mg/dL) | 44.4 + 11.9 | 42.7 + 10.7 | 48.1 + 13.6 | 0.01 |
| Triglycerides (mg/dL) | 211 + 120 | 220 + 125 | 191 + 105 | 0.18 |
| LDL cholesterol (mg/dL) | 1119 + 41 | 121 + 41.6 | 114 + 39.8 | 0.33 |
| Fasting glucose (mg/dL) | 126 + 55.5 | 129 + 55.9 | 117 + 53.8 | 0.14 |
| HbA1c | 6.93 + 2.09 | 7.12 + 2.19 | 6.37 + 1.69 | 0.11 |
| Iron (μg/dL) | 82.6 + 38.7 | 83.8 + 40.5 | 78.6 + 31.9 | 0.52 |
| Total iron binding capacity (μg/dL) | 322 + 72.3 | 319 + 74.6 | 335 + 63.4 | 0.31 |
| Ferritin (ng/mL) | 258 + 306 | 276 + 324 | 201 + 232 | 0.21 |
| Mallory bodies | 50 + 21.3 | 50 + 29.8 | 0 | < 0.01 |
| CAD | 67 + 28.9 | 50 + 29.9 | 17 + 26.2 | 0.63 |
| Gastric bypass | 21 + 8.94 | 14 + 8.33 | 7 + 10.4 | 0.61 |
| Cirrhosis | 14 + 5.96 | 14 + 8.33 | 0 | 0.01 |
| Steatosis | 1.92 + 0.861 | 2.1 + 0.83 | 1.46 + 0.765 | < 0.01 |
| Inflammation | 0.44 + 0.62 | 0.625 + 0.663 | 0 | < 0.01 |
| Fibrosis | 0.753 + 1.11 | 1.05 + 1.21 | 0 | < 0.01 |
| Ballooning | 0.821 + 0.712 | 1.15 + 0.575 | 0 | < 0.01 |
| NAS score | 3.18 + 1.69 | 3.86 + 1.45 | 1.46 + 0.765 | < 0.01 |
AST: Aspartate transaminase; ALT: Alanine transaminase; HDL: High-density lipoprotein cholesterol; NAS: Nonalcoholic fatty liver disease activity score; NASH: Nonalcoholic steatohepatitis; LDL: Low-density lipoprotein cholesterol; BMI: Body mass index; INR: International normalized ratio; CAD: Coronary artery disease.