Table 3.
Country | Ref. | Publication | Treatment duration | Patients | Therapy regimen | Eradication rate (ITT) | Eradication rate (PP) |
South Korea | Lim et al[104] | 2013 | 14 d | 78 | Rab 20 mg bid | 80.8% | 81.3% |
Amo 1 g bid | |||||||
Cla 500 mg bid | |||||||
Met 500 mg bid | |||||||
Lee et al[100] | 2015 | 7 d | 170 | Rab 20 mg bid | 79.4% | 94.4% | |
Amo 1 g bid | |||||||
Cla 500 mg bid | |||||||
Met 500 mg tid | |||||||
Thailand | Kongchayanun et al[188] | 2012 | 5 d/10 d | 55/55 | Rab 20 mg bid | 89.1%/96.4% | NA |
Amo 1 g bid | |||||||
Met 400 mg tid | |||||||
Cla 1 g qd | |||||||
Singapore | Ang et al[102] | 2015 | 10 d | 153 | PPI standard does | 81.7% | 95.4% |
Amo 1 g bid | |||||||
Cla 500 mg bid | |||||||
Met 400 mg bid | |||||||
Spain | Molina-Infante et al[97] | 2012 | 10 d | 209 | PPI standard does | 87.0% | 89.0% |
Amo 1 g bid | |||||||
Cla 500 mg bid | |||||||
Met 500 mg bid | |||||||
McNicholl et al[103] | 2014 | 10 d | 168 | Ome 20 mg bid | 87.0% | 91.0% | |
Amo 1 g bid | |||||||
Cla 500 mg bid | |||||||
Met 500 mg bid | |||||||
Latin America | Greenberg et al[106] | 2011 | 5 d | 489 | Lan 30 mg bid | 73.6% | NA |
Amo 1 g bid | |||||||
Cla 500 mg bid | |||||||
Met 500 mg bid |
ITT: Intention to treat; PP: Per protocol; NA: Not available; Lan: Lansoprazole; Amo: Amoxicillin; Cla: Clarithromycin; Met: Metronidazole; PPI: Proton pump inhibitor; Rab: Rabeprazole; Ome: Omeprazole.