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. 2015 Nov 6;6(4):183–198. doi: 10.4292/wjgpt.v6.i4.183

Table 3.

Helicobacter pylori eradication rates following first-line concomitant therapy

Country Ref. Publication Treatment duration Patients Therapy regimen Eradication rate (ITT) Eradication rate (PP)
South Korea Lim et al[104] 2013 14 d 78 Rab 20 mg bid 80.8% 81.3%
Amo 1 g bid
Cla 500 mg bid
Met 500 mg bid
Lee et al[100] 2015 7 d 170 Rab 20 mg bid 79.4% 94.4%
Amo 1 g bid
Cla 500 mg bid
Met 500 mg tid
Thailand Kongchayanun et al[188] 2012 5 d/10 d 55/55 Rab 20 mg bid 89.1%/96.4% NA
Amo 1 g bid
Met 400 mg tid
Cla 1 g qd
Singapore Ang et al[102] 2015 10 d 153 PPI standard does 81.7% 95.4%
Amo 1 g bid
Cla 500 mg bid
Met 400 mg bid
Spain Molina-Infante et al[97] 2012 10 d 209 PPI standard does 87.0% 89.0%
Amo 1 g bid
Cla 500 mg bid
Met 500 mg bid
McNicholl et al[103] 2014 10 d 168 Ome 20 mg bid 87.0% 91.0%
Amo 1 g bid
Cla 500 mg bid
Met 500 mg bid
Latin America Greenberg et al[106] 2011 5 d 489 Lan 30 mg bid 73.6% NA
Amo 1 g bid
Cla 500 mg bid
Met 500 mg bid

ITT: Intention to treat; PP: Per protocol; NA: Not available; Lan: Lansoprazole; Amo: Amoxicillin; Cla: Clarithromycin; Met: Metronidazole; PPI: Proton pump inhibitor; Rab: Rabeprazole; Ome: Omeprazole.