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. 2015 Oct 31;32(10):971–982. doi: 10.1007/s12325-015-0254-9

Table 2.

Clinical parameters and renal metrics at different furosemide dosages in the study populations

Parameters Group 1 (125 mg) (N = 14) Group 2 (250 mg) (N = 13) Group 3 (500 mg) (N = 13)
Normal saline Hypertonic saline P Normal saline Hypertonic saline P Normal saline Hypertonic saline P
SBP (mm Hg) 128 ± 14 117 ± 14 0.04 128 ± 19 119 ± 16 0.2 128 ± 15 118 ± 10 0.05
HR (beats/min) 76 ± 13 72 ± 9 0.3 82 ± 16 73 ± 13 0.1 81 ± 12 68 ± 7 0.003
Serum sodium (mEq/L) 141 ± 3 140 ± 3 0.4 138 ± 3 140 ± 2 0.05 140 ± 3 141 ± 2 0.32
BUN (mg/dL) 64 ± 26 60 ± 23 0.6 64 ± 32 79 ± 29 0.2 69 ± 35 87 ± 33 0.19
Creatinine (mg/dL) 1.1 ± 0.4 1.0 ± 0.4 0.5 1.2 ± 0.5 1.2 ± 0.3 1 1.2 ± 0.4 1.4 ± 0.4 0.21

Values are presented as mean ± standard deviation. Normal saline (0.9%) and hypertonic Saline (1.4%). BUN blood urea nitrogen, HR heart rate SBP systolic blood pressure