Table 3. Multivariate analysis of clinical outcome in 52 patients who achieved CR after induction therapy.
|
Overall survival |
Relapse-free survival |
|||
|---|---|---|---|---|
| HR (95% CI) | P-value | HR (95% CI) | P-value | |
| Single monosomy | 0.314 (0.135–0.732) | 0.007 | 0.237 (0.092–0.615) | 0.003 |
| WBC <50 × 109/l | — | — | 0.177 (0.050–0.628) | 0.007 |
| De novo AML | — | — | 0.098 (0.024–0.404) | 0.001 |
| Absence of abn(17p) | — | — | 0.435 (0.164–1.152) | 0.179 |
| Allo-HSCT in CR | 0.268 (0.090–0.798) | 0.018 | 0.249 (0.099–0.626) | 0.003 |
Abbreviations: Allo-HSCT, allogeneic hematopoietic stem cell transplantation; AML, acute myeloid leukemia; CI, confidence interval; CR, complete remission; HR, hazard ratio; WBC, white blood cell count.