Table 1. Baseline characteristics.
Patients N=33 | |
---|---|
Age, years, median (range) | 59 (32–78) |
Age <50 years, N (%) | 7 (21) |
Female sex, N (%) | 12 (36) |
Hemoglobin, median (range), g/dl | 11.5 (7.5–15.6) |
Hemoglobin <9 gm/dl, N (%) | 1 (9) |
Serum creatinine, median (range), mg/dl | 0.9 (0.6–1.3) |
Serum calcium, median (range), mg/dl | 9.7 (8.5–13) |
Calcium >11.0 mg/dl, N (%) | 2 (7) |
Lactate dehydrogenase, median (range), mg/dl | 150 (95-206) |
Beta-2 microglobulin, median (range), μg/ml | 3.73 (1.37–10.9) |
Beta-2 microglobulin, >3.5 μg/ml | 17 (52) |
Monoclonal protein type | |
IgG | 22 (67) |
IgA | 7 (21) |
FLC only | 4 (12) |
Serum monoclonal protein spike, median (range), g/dl | 2.8 (0.0–6.0) |
Serum monoclonal protein spike, >3.0 g/dl | 16 (48) |
Urine monoclonal protein spike, median (range), g/dl | 0.1 (0.0–4.7) |
Not present | 12 (36) |
Detected on immunofixation only | 4 (12) |
Measurable but <0.5 g/24 h | 12 (33) |
⩾0.5 g/24 h | 5 (15) |
BMPC percentage, median (range) | 40 (2–90) |
BMPC >60% | 12 (36) |
Serum FLC assay | |
Involved FLC, median (range), mg/dl | 10.2 (0.4–929) |
Involved/uninvolved ratio | 33.2 (0.938–1206.66) |
Involved/uninvolved FLC level⩾100 mg/dl | 6 (18) |
Involved/uninvolved FLC ratio⩾100 | 9 (27) |
Abbreviations: BMPC, bone marrow plasma cell; FLC, free light chain.