Table 2. Distribution of primary cytogenetic categories.
| Molecular cytogenetic classification | All patients in whom cytogenetic studies were done (n=28) | Patients with informative cytogenetic results (n=24) |
|---|---|---|
| No. of patients (%) | No. of patients (%) | |
| Trisomiesa | 19 (68) | 18 (75) |
| t(11;14)(q13;q32) | 2 (7) | 2 (8) |
| t(4;14)(p16;q32) | 0 (0) | 0 (0) |
| MAF translocations [t(14;16)(q32;q23) and t(14;20)(q32;q11)] | 0 (0) | 0 (0) |
| Other/unknown IgH translocation partner | 0 (0) | 0 (0) |
| Both IgH translocation and trisomiesb | 1(4) | 1 (4) |
| Monosomy13/del(13q) in the absence of IgH translocation or trisomiesc | 3 (11) | 3 (13) |
| Normal or insufficient plasma cells | 4 (14) | NA |
Abreviations: FISH, fluorescent in situ hybridization; NA, not applicable.
Trisomies were detected on baseline FISH studies in 18 of 19 patients (includes 1 patient with tetrasomy 11) and by metaphase cytogenetics in 1 patient.
This patient had t(11;14) and trisomies.
Includes one patient with concurrent monosomy 14.