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| Risk stratification | Cytogenetic abnormalities |
|---|---|
| Standard riska | Trisomies t(11;14) t(6;14) |
| Intermediate riska | t(4;14) Gain(1q21) |
| High risk | Del(17p) t(14;16) t(14;20) Del(1p) |
Modified from Rajkumar.1
Presence of del 17p indicates high risk MM regardless of other abnormalities; gain(1q21) (without other high risk abnormalities) is considered intermediate-risk.
