FIGURE 1.
Fibrillarin sequence comparison relationships of taxa. The analysis included the sequences from both Arabidopsis thaliana fibrillarin (AtFib1 NP_568772.3 and AtFib2 NP_567724.1), fibrillarin sequence from Brassica oleracea (BoFib Bol039546), fibrillarin sequence from Homo sapiens (HsFib CAA39935.1) and the yeast fibrillarin Nop1 CAA98572.1. All the domains are label in different colors Gar domain in blue, space region in gray, central domain in purple and the alpha rich domain in orange. Arginines known to be methylated are marked in a red circle. Key amino acids that were mutated in Nop1 are marked in red. The phosphorylated serine is marked in a yellow square and the acetylated lysine in a black square. The doted underline sequence marks the methyl transferase domain. The slash boxes in green indicate the RNA binding domains in Arabidopsis thaliana fibrillarins. Green label amino acids indicate the define RNA binding region.
