Figure 9.

Representative pictures at light microscopy of semi-thin sections from gastrocnemius muscle. Semi-thin sections were stained with methylene and toluidine blue. Vehicle- and lithium-treated WT mice and lithium-treated G93A mice exhibit longitudinal, regular, parallel arrangement of aligned muscle fibers showing the typical banding pattern. Nuclei at the periphery of the fibers are visible (arrowheads). Muscle from vehicle-treated G93A mice shows unparalleled and disarranged fibers and myofibrils. In this latter group the space among fibers appears enlarged (arrow). Scale bar: 28 μm.