Table 2. Subject scores of PDRP–ALFF networks and ROC parameters in patients with PD and normal controls.
|
Subject scores |
ROC parameters |
|||
|---|---|---|---|---|
| Normal | PD | AUC | Sensitivity/specificity (%) | |
| Cohort A | 0.00±0.14 | 2.02±0.10 | 0.968±0.013 | 91.4/88.9 |
| Cohort B | 0.00±0.19 | 1.49±0.09 | 0.921±0.034 | 82.1/78.6 |
| Cohort C | 0.55±0.12 | 1.08±0.08 | 0.782±0.061 | 70.0/69.2 |
Abbreviations: ALFF, amplitude of low-frequency fluctuation; AUC, the area under the curve; PDRP, Parkinson's disease–related pattern; ROC, receiver operating characteristic.
Subject scores and AUC values are presented as mean±s.e.m. The values marked in italics indicate the cohorts used to identify the PDRP–ALFF brain networks. In each cohort, subject scores for the corresponding brain network were elevated in the PD patients compared with the normal controls (P<0.00001).