Figure 4.

Local analysis: contrast and reproducibility. The mean and s.d. of white matter (WM)/gray matter (GM) contrast values for Logan distribution volume ratio (DVR) and standardized uptake value (SUV) analysis are reported as function of the positron emission tomography (PET) reconstruction setting and simulated region dimensions (A and B, respectively). Similarly, the mean local test/retest reproducibility is also shown for both GM and WM as obtained with Logan (C and E) and SUV (D and F).