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. 2015 Jun 10;35(11):1783–1789. doi: 10.1038/jcbfm.2015.123

Figure 1.

Figure 1

Ketones improved neurologic function after stroke. At 24 hours after middle cerebral artery (MCA) occlusion. (A) Ketones reduced neurologic score (0 means no deficits; 4 complete paralysis). (B) In the accelerating rotarod test, ketones improved the ability to stay on the rod (latency to fall, in seconds). (C) In the open field test, ketones increased the ability to explore around (total distance, in centimeters). Data were presented as mean±s.e.m., *P<0.05, **P<0.01 compared with NS group. NS=0.9% normal saline treatment, n=10; Ketones=ketones treatment (BHB, 0.4 mmol/kg and ACA 0.45 mmol/kg, n=9). ACA, acetoacetate; BHB, beta-hydroxybutyrate.