Table 2. Correlations between age and BPND of [11C]-(+)-PHNO.
| Substantia nigra | Hypothalamus | Ventral pallidum | Globus pallidus | Ventral striatum | Caudate | Putamen | |
|---|---|---|---|---|---|---|---|
| Correlations between age and BPND of [11C]-(+)-PHNO | |||||||
| r | 0.00 | −0.10 | 0.19 | −0.07 | −0.23 | −0.32 | −0.19 |
| P-value | 0.99 | 0.45 | 0.15 | 0.58 | 0.05 | 0.005 | 0.12 |
| Partial correlations between age and BPND of [11C]-(+)-PHNO controlling for gender | |||||||
| r | 0.00 | −0.11 | 0.23 | −0.07 | −0.23 | −0.33 | −0.19 |
| P-value | 0.99 | 0.43 | 0.08 | 0.58 | 0.06 | 0.006 | 0.12 |
BPND, binding potential nondisplaceable. Correlation analyses were performed to determine the association between age and BPND with [11C]-(+)-PHNO in each region, including the substantia nigra and hypothalamus, which represent specific D3 receptor regions, the globus pallidus and ventral pallidum, which represent preferential D3 receptor regions, and the caudate and putamen, which represent specific D2 receptor regions. Partial correlation analyses were performed to determine the association between age and BPND with [11C]-(+)-PHNO in each region, controlling for gender. The numbers of subjects were 72 for the substantia nigra, globus pallidus, ventral striatum, caudate, and putamen, and 60 for the hypothalamus and ventral pallidum. Bold characters=statistically significant.