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. 2015 Jun 24;35(11):1862–1870. doi: 10.1038/jcbfm.2015.145

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Copyright © 2015 International Society for Cerebral Blood Flow & Metabolism, Inc.

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Scatterplots of metabolite parameters with control data are shown. For all plots, the indicated regression line (solid) and 95% confidence intervals (dashed) for the means are shown if significant. Data plotted in red are from 1.5 hours (also, open symbols), plotted in blue are 3-hour data (also, filled symbols). Control data mean and s.d. are plotted; none of the control data showed any significant regression values. (A) Glutamate/total creatine (Glu/tCr) with N-acetylaspartate (NAA)/tCr 3-hour group, R=+0.86, P<0.001; 1.5-hour group, R=+0.51, P<0.05. (B) GABA/tCr with NAA/tCr 3-hour group, R=+0.51, P<0.05; 1.5-hour group, +0.64, P<0.005. (C) CA3 T2 with myo-inositol/tCr (Ins/tCr) 3-hour group, R=−0.63, P<0.005; 1.5-hour group, R=−0.68, P<0.02. (D) Glutamine/tCr (Gln/tCr) with Glu/tCr 3-hour group, R=+0.45, nonsignificant with P=0.08; 1.5-hour group, R=+0.53, P<0.05. The combined mean and s.d. of the 1.5- and 3-hour groups for Glu/tCr and Gln/tCr are also shown (see text). (E) Gln/tCr with Glutathione/tCr (GSH/tCr) 3-hour group, R=−0.66, P<0.01; 1.5-hour group nonsignificant. GABA, gamma-aminobutyric acid.