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. 2015 Oct 12;36(11):1327–1336. doi: 10.1038/aps.2015.75

Figure 2.

Figure 2

Ketamine (Ket) inhibited ATX-augmented INaL in a concentration-dependent manner. (A) Representative whole-cell recordings of INaL in the absence of drug (Control) and in the presence of ATX (30 nmol/L) before or after the application of Ket (20, 40, or 80 μmol/L). (B) The current-voltage relationship for INaL. (C) Summary data for the mean current density of INaL (at −20 mV) in the absence (Control) and presence of ATX and ATX plus Ket. The data are expressed as the mean±SD (n=8). cP<0.01 vs Control; fP<0.01 vs 30 nmol/L ATX; iP<0.01 vs ATX plus Ket 20 μmol/L; lP<0.01 vs ATX plus Ket 40 μmol/L.