Figure 5.

Sleep-stage distributions in normal mice and PSNL mice after the intraperitoneal administration of gelsemine. (A) Changes in the time course in NREM sleep, REM sleep, and wakefulness after the ip administration of 4 mg/kg gelsemine to normal mice and PSNL mice. Each data dot represents the hourly mean time spent in each stage. (B) Effect of gelsemine on the total time spent in NREM sleep, REM sleep, and wakefulness for 3 h after administration to normal mice and PSNL mice. Data are expressed as mean±SEM (n=6–7). ^cP<0.01 vs vehicle-treated normal mice.