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Effect of gelsemine on the motor performance of mice in the rota-rod test. (A) Time course of the effects of gelsemine and pregabalin on the rota-rod staying time of PSNL mice. (B) Dose-dependent effects of gelsemine on the rota-rod staying time of PSNL mice. The mean time (s) mice remained on the rota-rod was measured 2 h after the ip administration of gelsemine, pregabalin (reference drug) or vehicle. Data are expressed as mean±SEM (n=6–8). cP<0.01 vs vehicle-treated PSNL mice.
